None listed
Conditions
Interventions
None listed
Sponsors
Yonsei University Health System, Severance Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Males or females aged 20 years or older 2. Patients with no history of taking lipid-lowering medications for at least the past 3 months 3. Individuals with triglycerides (TG) = 80 mg/dL and high-density lipoprotein (HDL) cholesterol = 60 mg/dL, or a TG/HDL ratio of = 1 4. For patients with type 2 diabetes, those with carotid imaging within the past 2 years showing less than 50% carotid artery stenosis
Exclusion criteria
Exclusion criteria: 1. Patients with a history of coronary artery disease (=30% coronary artery stenosis, angina, or myocardial infarction) 2. Patients with a history of atherosclerotic ischemic stroke or transient ischemic attack, or those with corresponding findings on brain imaging 3. For patients with type 2 diabetes, those with carotid imaging within the past 2 years showing =50% carotid artery stenosis 4. Patients with a history of peripheral artery disease, those with imaging findings indicating peripheral artery occlusion, or an ankle-brachial index (ABI) < 0.9 5. Patients with an abdominal aortic aneurysm 6. Individuals deemed ineligible for clinical trial participation by the investigator or those unable to read the consent form (e.g., illiterate individuals, non-native speakers)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in the proportion of LDL-C subfraction small size between LMHR subjects (statin user group vs. non-user group) | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean values of LDL cholesterol and LDL-particle size;Coronary artery calcium score | — |
Countries
Korea, Republic of
Contacts
Public ContactByungwan Lee
Yonsei University Health System, Severance Hospital
Outcome results
None listed