None listed
Conditions
Interventions
Procedure/Surgery : The test group undergoes follow-up observation by performing surgery along with nerve trunk transplantation using acellular allogeneic nerves during functional free muscle flap tra
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adults between 19 and 79 years of age 2) Patients diagnosed with House-Brackmann Grade levels 2 to 6 3) Patients eligible for functional free muscle transplantation 4) Patients with normal facial nerve function on one side
Exclusion criteria
Exclusion criteria: 1) Patients being treated for a serious infectious disease or immune disease 2) Within 2 weeks of the screening visit, patients who have used drugs that may affect the effectiveness evaluation at the discretion of the researcher, such as antithrombotic agents, steroid drugs including oral preparations and ointments, botox, fillers, etc. 3) Patients undergoing anticancer or immunosuppressant treatment 4) Patients diagnosed with bilateral facial paralysis 5) Participation in another clinical study within 2 months from the date of the screening visit (However, participation is possible if other clinical trials in which the participant participated do not affect this study at the discretion of the researcher) 6) In cases where participation in clinical research is inappropriate in the judgment of other researchers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in score on Facial Nerve Grading System 2.0 scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in score on Facial Nerve Grading System 2.0 scale;Change in movement of the orbicularis oculi muscle using a 3D rendering program;Change in distance symmetry of the orbicularis oculi muscle using a 3D rendering program;Change in angular symmetry of the orbicularis oculi muscle using a 3D rendering program | — |
Countries
Korea, Republic of
Contacts
Public ContactTaeseok Oh
Asan Medical Center
Outcome results
None listed