None listed
Conditions
Interventions
Dietary Supplement : • Pinus koraiensis Siebold & Zucc extract powder group: once a day, 1 capsule once, after dinnerfor, a duration of 8 weeks(680 mg/day, 480 mg/day for Pinus koraiensis Siebold & Zu
Sponsors
Wonkwang University Oriental Medical Hospital, Jeonju
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Males and females aged 19 years or older and 60 years or less at the screening examination 2) Participants with score of 27 or higher on the Fatigue Severity Scale (FSS) 3) Participants who have fully understand the information provided about the study voluntarily decided to participate and agree to comply with precautions
Exclusion criteria
Exclusion criteria: 1) Patients whose BMI is 18.5 kg/m^2 under or 35 kg/m^2 or over at the screening examination 2) Patients who have clinically significant acute or chronic cardio-cerebrovascular systems, endocrine systems, immune systems, respiratory systems, hepatic biliary systems, kidneys and urinary systems, neuropsychiatric systems, musculoskeletal systems, inflammatory and hematologic and tumorigenic, gastrointestinal diseases, etc. 3) Patients with uncontrolled hypertension 4) Patients with uncontrolled diabetes(HbA1c>7%) 5) Patients with insomnia 6) Patients unable to perform an exercise 7) Patients with a history of significant hypersensitivity reaction to the ingredients of Pinus koraiensis Siebold & Zucc or Pinus koraiensis Siebold & Zucc lesf ingredients 8) Patients who have taken medicines, herbal medicines, or health functional foods related to improving fatigue within 1 month before screening 9) Patients who have taken exercise-enhancing supplements within 2 weeks prior to the screening test 10) Patients who have received antipsychotic drug treatment within 2 months prior to screening test 11) Patients with or suspected of alcoholism or drug abuse 12) Patients who participated in other human application tests within 3 months prior to screening test 13) pregnant or lactating women 14) Women of childbearing potential who do not accept the practice of adequate contraception 15) Patients who are judged ineligible to participate in the trial by the principal investigator for other reasons, including laboratory test outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue severity scale;Time and distance to exhaustion | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood fatigue indicators;Exercise Stress Testing;Rating of perceived exertion;Visual Analogue Scale;grip strength | — |
Countries
Korea, Republic of
Contacts
Public ContactJoo Jongcheon
Wonkwang University Oriental Medical Hospital, Jeonju
Outcome results
None listed