Differences in the occurence of metabolic acidosis in blood when propofol and sevoflurane are used as anesthetic

the occurrence of Metabolic Acidosis when using PROpofol and Sevoflurane as anesthetics in patients; a pilot study of the prospective comparative study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0010130

Enrollment

100

Registered

2025-01-10

Start date

2024-12-15

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Intraoperative neuromonitoring is a technique that uses electrophysiological methods to monitor the patients nervous system during surgery. Through this monitoring, surgeons can detect nerve da

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective neurosurgery 2. Patients aged 19 to 80 years, and corresponding to the American Society of Anesthesiologists physical status classification system II-IIIe

Exclusion criteria

Exclusion criteria: 1. Patients who do not consent to a clinical trial 2. Patients with underlying sepsis or expected massive bleeding 3. Patients with moderate-to-high risk lung disease such as asthma or chronic obstructive pulmonary disease 4. Patients who are chronic alcoholics or are taking long-term psychotropic medications 5. Patients with acidosis in preoperative ABGA

Design outcomes

Primary

Measure	Time frame
Rate of occurrence of severe metabolic acidosis with propofol or sevoflurane	—

Secondary

Measure	Time frame
Rate of occurrence of mild metabolic acidosis with propofol or sevoflurane;Duration from onset of anesthesia to onset of metabolic acidosis;Type and amount of pressor used during anesthesia;Amount of fluid infused per hour;Amount of Blood loss and red blood cell transfusion;Average hourly urine output;Anesthesia time and intubation and extubation time;ICU transfer rate and length of stay;Complication;mortality	—

Measure

Time frame

Rate of occurrence of mild metabolic acidosis with propofol or sevoflurane;Duration from onset of anesthesia to onset of metabolic acidosis;Type and amount of pressor used during anesthesia;Amount of fluid infused per hour;Amount of Blood loss and red blood cell transfusion;Average hourly urine output;Anesthesia time and intubation and extubation time;ICU transfer rate and length of stay;Complication;mortality

—

Countries

Korea, Republic of

Contacts

Public ContactEunji Ko

Korea University Anam Hospital

froken_ko@naver.com+82-2-920-5632

Outcome results