None listed
Conditions
Interventions
Dietary Supplement : Subjects take placebo or DEFENDUM® PROBIOTICS once a day for 12 weeks.
Sponsors
Maeil Health Nutrition
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subject who voluntarily agrees to participate and signs in informed consent form 2) Healthy people, 20 = age < 70. 3) Subject who had symptoms of upper respiratory tract infection more than twice a year before 2019
Exclusion criteria
Exclusion criteria: 1) White blood cell AND absolute neutrophil count exceed normal range. 2) Patients who was diagnosed and are currently in the treatment of diabetes 3) Those who have taken antibiotics within 2 months of the first visit or are likely to take it during the study 4) Subjects who are currently in the treatment of significant clinical disease related to acute or chronic cardiovascular system, immune system, respiratory system, liver biliary, kidney and urinary tract, nervous system, musculoskeletal disorders, psychic, infection and blood neoplastic. 5) Subjects who have medical history with myocardial infarction or cerebrovascular disease within 6 months. 6) Subjects who have a neurologically or psychologically important medial history or who is currently suffering from a disease. 7) Subjects who have uncontrolled high blood pressure. 8) Subjects whose AST or ALT exceeds 3 times of normal range. 9) Subjects whose creatinine exceeds 2 times of normal range. 10) Subjects who have complained of severe gastrointestinal symptoms such as heartburn, indigestion. 11) Subjects who got a vaccination within 1 months before screening. 12) Excessive smoker 13) Subjects who usually consume alcohol as follows - men: 210g/week, women 140g/week 14) Subjects whose BMI is under 18.5 or exceeds 30.0 15) Subjects with a low level of stress 16) Subjects who continue to consume probiotics or prebiotics within one month of their first visit 17) Subjects who have intaken or is intaking functional foods 18) Subjects who are planning to participate other studies within one month of their first visit 19) Subjects who are pregnant or breastfeeding or planning a pregnancy. 20) Subjects who are sensitive to test foods/algae or have food allergies. 21) Subjects who are deemed to be inappropriate to this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NK cell activity (%) | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event;bowel habit | — |
Countries
Korea, Republic of
Contacts
Public ContactMinju Kim
Seoul Metropolitan Government Seoul National University Boramae Medical Center
Outcome results
None listed