None listed
Conditions
Interventions
Dietary Supplement : • TCG24-12(high content of Effective Microorganisms, gochujang powder): 2 times a day, 3 packs once, after breakfast/dinner, a duration of 4 weeks(25.3 g/day, 19 g/day for gochuja
Sponsors
Jeonbuk National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Males and females aged over 50 screening examination 2) Participants who had symptoms of upper respiratory infection (cold, tonsillitis, pharyngitis, laryngitis, sinusitis, otitis media, rhinitis, etc.) at least twice within 12 months before screening examination 3) Participants who have fully understand the information provided about the study voluntarily decided to participate and agree to comply with precautions
Exclusion criteria
Exclusion criteria: 1) Patients who have received influenza vaccination within 1 month before the screening test 2) Patients whose BMI is 18.5 kg/m^2 under or 35 kg/m^2 or over at the screening examination 3) Patients who have clinically significant acute or chronic cardio-cerebrovascular systems, endocrine systems, immune systems, respiratory systems, hepatic biliary systems, kidneys and urinary systems, neuropsychiatric systems, musculoskeletal systems, inflammatory and hematologic and tumorigenic, gastrointestinal diseases, etc. 4) Patients who have received anti-psychotic medication within three months before screening examinations 5) Patients with a history of significant hypersensitivity reaction to the ingredients of red pepper and red pepper paste ingredients 6) Patients who have or are suspected of alcoholism or substance abuse 7) Patients who have participated in other clinical trials within 3 months prior to the screening examination 8) Women who are pregnant or breastfeeding 9) Patients who have not accepted the implement of appropriate contraceptive method among women who are fertile 10) Patients who are judged ineligible to participate in the trial by the principal investigator for other reasons, including laboratory test outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of intestinal microbiome | — |
Secondary
| Measure | Time frame |
|---|---|
| Natural Killer cell activity;Cytokines;Fatigue Severity Scale;Patient global assessment;Inflammatory index;Short-chain fatty acids in feces | — |
Countries
Korea, Republic of
Contacts
Public ContactSoo Wan Chae
Jeonbuk National University Hospital
Outcome results
None listed