None listed
Conditions
Interventions
None listed
Sponsors
L&C BIO
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) 61 years to 65 years 2) Patients or legal representatives who voluntarily decide to participate in the clinical trial, after which sign the consent form. 3) Defect: International Cartilage Repair Society(ICRS) Grade III or IV single defect chondral lesion on knee cartilage 4) Patients whose primary lesion site can be designated as one section of the knee joint, and the area can be determined as the main cause of clinical symptoms 5) knee cartilage defect size : above 1.5?, below 10 ?
Exclusion criteria
Exclusion criteria: 1) Patients who have autoimmune diseases (Ex. Rheumatoid arthritis) 2) Patients who underwent surgery related to cartilage defect treatment, such as microfracture, autologous chondrocyte therapy within the past 1 year (Possible for HTO surgery) 3) When screening, Patients who received intra-articular hyaluronic acid or steroid injections in the knee within 1 months 4) Patients who can’t take MRI scan 5) BMI index : 35kg/m2 or over
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MOCART score assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| IKDC score assessment;VAS score assessment;KOOS score assessment ;Collecting abnormal cases | — |
Countries
Korea, Republic of
Contacts
Public ContactKi-Mo Jang
Korea University
Outcome results
None listed