None listed
Conditions
Interventions
Drug : Study drug is prepared by a investogator in the seperate pharmacy. This study drug is admistered intravenously after general anesthesia induction to ensure patient blindness.
Control group: d
Sponsors
Samsung Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients undergoing arthroscopic shoulder surgery who are receiving pain control with brachial plexus block. - American Society of Anesthesiologists physical criteria I, II: ex) Healthy adults without underlying diseases (I), patients with systemic diseases such as controlled hypertension or controlled diabetes that can be controlled with medication or surgical treatment (II)
Exclusion criteria
Exclusion criteria: - American Society of Anesthesiologists physical criteria III, IV, V: ex) Patients with systemic diseases such as diabetes with complications (III), Patients with extremely serious systemic diseases requiring immediate treatment (IV), Death (V) - Pregnant or lactating women - Patients with serious blood coagulation disorders (INR 1.5 or higher on the last blood coagulation test before surgery) - Patients with unstable coronary artery disease, congestive heart failure, arrhythmia, or myocarditis - Patients with cerebrovascular disease - Patients with systemic infection, current infection in the area where brachial plexus block will be performed (neck area) - Patients who do not understand this study and express their intention not to participate in the study - Patients with allergies to local anesthetics - Patients with contraindications to the test drugs (dexamethasone disodium phosphate and dexamethasone palmitate) * Patients with hypersensitivity to this drug or its components or a history of hypersensitivity * Lactating women * Hypersensitivity to soybean oil or Patients with a history of allergies * Patients with hypersensitivity to soybeans or peanuts * Patients with intra-articular, intrabursal, intra-tendon, or peri-tendon infections * Patients with joint instability * Patients receiving live vaccines * Patients with herpes simplex, shingles, or chickenpox * Patients with infections for which there are no effective antimicrobial agents, systemic fungal infections - Patients who have failed brachial plexus block
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain intensity during 24 h after brachial plexus block (Weighted AUC = [Area under curve of pain score at 4h 8h 12h 24h]/24) | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores before and after brachial plexus block (at rest and during mobilization);Worst pain score during 48 h after brachial plexus block;opioid comsumption;Time to lock resolution;Patient satisfaction for fist night sleep quality, and postoperative analgesia for 24h after surgery;nausea and vomiting after brachial plexus block ;dizziness after brachial plexus block ;respiratory depression after brachial plexus block | — |
Countries
Korea, Republic of
Contacts
Public ContactYu Jeong Bang
Samsung Medical Center
Outcome results
None listed