Skip to content

A Clinical trial to evaluate the cartilage regeneration efficacy and safety of MegaCarti® in patients aged 50 to 60 years with knee cartilage defects : Multicenter observational study

A Clinical trial to evaluate the cartilage regeneration efficacy and safety of MegaCarti® in patients aged 50 to 60 years with knee cartilage defects : Multicenter observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0010005
Enrollment
32
Registered
2024-12-06
Start date
2023-12-29
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Korea University Anam Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) 50 years to 60 years 2) Patients or legal representatives who voluntarily decide to participate in the clinical trial, after which sign the consent form. 3) Defect: International Cartilage Repair Society(ICRS) Grade III or IV single defect chondral lesion on knee cartilage 4) Patients whose primary lesion site can be designated as one section of the knee joint, and the area can be determined as the main cause of clinical symptoms 5) knee cartilage defect size : Above 1.5? , below 10 ?

Exclusion criteria

Exclusion criteria: 1) Patients who have autoimmune diseases (Ex. Rheumatoid arthritis) 2) Patients who underwent surgery related to cartilage defect treatment, such as microfracture, autologous chondrocyte therapy within the past 1 year (Possible for HTO surgery) 3) When screening, Patients who received intra-articular hyaluronic acid or steroid injections in the knee within 1 months 4) Patients who can’t take MRI scan 5) BMI index : 35kg/m2 or over

Design outcomes

Primary

MeasureTime frame
MOCART score assessment

Secondary

MeasureTime frame
VAS score assessment;KOOS score assessment;Collecting abnormal cases;IKDC score assessment

Countries

Korea, Republic of

Contacts

Public ContactKi-Mo Jang

Korea University

kimo98@hanmail.net+82-2-920-6566

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Mar 14, 2026