A multicenter randomized controlled study to evaluate the efficacy of a 12-week digital cognitive intervention in patients with mild cognitive impairment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0009920

Enrollment

120

Registered

2024-11-11

Start date

2024-09-30

Completion date

Unknown

Last updated

2024-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : Conventional training group will perform cognitive training at home using a paper-and-pencil cognitive intervention program for 12 weeks, 5 days a week. Alzguard training group will acces

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients aged 60 and above who: 2. Can read and write. 3. Are capable of using a smartphone. 4. Mild cognitive impairment judgment criteria - Patients diagnosed with mild cognitive impairment according to the Petersen criteria (2003) - The subject or caregivers complain about memory decline. - The delayed recall score of the Seoul Verbal Learning Test (SVLT) is lower than -1 standard deviation (SD) compared to the age, sex and education matched norm. - The score of K-MMSE is over -1.5 SD compared to the age, sex and education matched norm. - Global CDR is 0.5 and the memory item score is 0.5 or 1. - Seoul-Instrumental Activities of Daily Living score is lower than 7. - Should not be dementia in the judgment of the clinician. - No other brain lesions that could cause memory decline were observed on brain CT or MRI. - If cognitive enhancement drugs were being used, the dosage was maintained without changes for at least 3 months prior to participating in this study.

Exclusion criteria

Exclusion criteria: 1. There are present or past major physical, neurological, or psychiatric disorders through history taking, physical examination, and laboratory test. 2. Having internal medicine disease or surgical disease such as cancer. 3. Having brain disease such as ischemic and hemorrhagic cerebral infarction. 4. Those who cannot read or write because of no education or illiteracy.

Design outcomes

Primary

Measure	Time frame
CANTAB(Cambridge Neuropsychological Test Automated Battery)	—

Secondary

Measure	Time frame
Modified ADAS-Cog(Alzheimer's Disease Assessment Scale-Cognitive Subscale);Self-report Questionnaire	—

Countries

Korea, Republic of

Contacts

Public ContactBori Kim

Ewha Womens University

bori.r.kim@gmail.com+82-2-2650-5847

Outcome results