None listed
Conditions
Interventions
Procedure/Surgery : Hyperbaric oxygen therapy (HBOT) will be administered through the O2 Fresh M50 (HBOT Medical, Wonju, South Korea) chamber, allowing the patient to breathe 100% oxygen. Upon enterin
Sponsors
CHA University Ilsan Medical Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Between the ages of 19 and 69 Patients with biopsy confirmed invasive breast cancer Patients who have undergone breast-conserving surgery for the purpose of tumor resection and require adjuvant radiotherapy or have undergone adjuvant radiotherapy within 5 times. When lymph nodes are included in the required irradiation range The Eastern Cooperative Oncology Group (ECOG) performance status 0-1 Those who understand the content of the study, agree to participate in the study, and provide written informed consent
Exclusion criteria
Exclusion criteria: Subjects with distant metastases of cancer Those whose cancer has invaded the skin of the breast (T4) or who have unhealed wounds on the skin Patients who have a history of radiotherapy of the cervical thoracic region for other reasons in the past Patients with a history of connective tissue disease Subjects with uncontrolled diabetes with HbA1c 7.0 or higher Pneumothorax and symptomatic upper respiratory tract infection If it is judged that there will be a significant decrease in respiratory function Undergoing treatments known to interact with hyperbaric oxygen therapy, such as cisplatin, doxorubicin, bleomycin, disulfiram, etc. When it is judged that diseases other than cancer (dementia, cerebrovascular disease, severe renal failure, etc.) may have a significant effect on the decline of physical function. If it is determined that the life expectancy is not sufficient follow-up within 3 months. Pregnant and lactating women Other persons who are judged by the researcher to be unsuitable for research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of grade 2 or more dermatitis according to RTOG toxicity scale | — |
Secondary
| Measure | Time frame |
|---|---|
| radiation therapy oncology group grade (RTOG grade) ;Modified 10-point Catterall skin scoring profile (CSSP);skindex-29;EORTC-QLQ-C30;numeric rating scale | — |
Countries
Korea, Republic of
Contacts
Public ContactJee Young Lee
CHA University Ilsan Medical Center
Outcome results
None listed