Skip to content

Effect of opioid-free anesthesia on postoperative nausea and vomiting in patients undergoing breast surgery

Effect of opioid-free anesthesia on postoperative nausea and vomiting in patients undergoing breast surgery: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0009829
Enrollment
80
Registered
2024-10-10
Start date
2024-09-02
Completion date
Unknown
Last updated
2024-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : In the OFA group, after the patient is admitted, dexmedetomidine 1ug/kg IBW is infused over 10 minutes, then propofol is injected, and IV lidocaine 1.5mg/kg is administered along w

Sponsors

Konyang University Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Both conditions below must be satisfied. 1. Female patient between 19 and 70 years of age 2. Patients ranked 1 to 3 according to the American Society of Anesthesiologists’ physical classification.

Exclusion criteria

Exclusion criteria: Excluded if any of the criteria below apply. - If reoperation was performed within 48 hours after surgery - Patient discharged the same day - Patients who received mechanical ventilation after surgery - Patients with contraindications to drug use in the test and control groups - If you have a psychiatric history or cognitive impairment - Patients with a long-term history of taking narcotic painkillers - Those who do not understand the purpose of the research or do not wish to participate in the research - If other researchers are deemed unsuitable

Design outcomes

Primary

MeasureTime frame
PONV

Secondary

MeasureTime frame
Whether or not PONV occurred in the recovery room, the type and total dose of antiemetics administered up to the second day after surgery, the amount of IV PCA used up to 24 hours after surgery, the type and amount of analgesics used after surgery, pain at the surgical site until the second day after surgery NRS scale, occurrence of complications of III or higher according to Clavien Dindo classification, time until first use of PCA, severity of PONV, length of hospital stay

Countries

Korea, Republic of

Contacts

Public ContactJi-Yoon Jung

Konyang University Hospital

jiyooning1030@gmail.com+82-42-600-9317

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Jun 11, 2026