The effect of opioid-free anesthesia on the incidence of catheter-related bladder discomfort

Effects of opioid-free anesthesia on postoperative catheter-related bladder discomfort in patients undergoing gynecological surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0009719

Enrollment

100

Registered

2024-08-23

Start date

2024-09-02

Completion date

Unknown

Last updated

2024-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Compare the incidence of catheter-related bladder discomfort (CRBD) between opioid-free anesthesia and conventional opioid-based anesthesia.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Participants who voluntarily decide to participate after obtaining written informed consent. 2) Patients aged 20 to 75 years. 3) Patients undergoing general anesthesia for gynecological surgery. 4) Patients with a urinary catheter in place for at least 6 hours after the end of surgery. 5) Relatively healthy patients classified as physical status 1-3 by the American Society of Anesthesiologists.

Exclusion criteria

Exclusion criteria: 1) Bladder dysfunction; overactive bladder, neurogenic bladder, bladder outlet obstruction. 2) Severe bradycardia (heart rate below 45 beats per minute), sick sinus syndrome, second-degree or higher atrioventricular block. 3) Severe liver dysfunction. 4) Severe renal dysfunction. 5) Immunocompromised individuals. 6) Stroke occurring within the past 6 months. 7) Dependence on alcohol or psychoactive drugs. 8) Patients with neuropsychiatric disorders (schizophrenia, epilepsy, Parkinson's disease, dementia). 9) Patients with communication difficulties. 10) Patients classified as physical status 4 or higher by the American Society of Anesthesiologists. 11) Pregnant women: For women of childbearing age, a pregnancy test must be conducted prior to study participation to confirm. 12) Patients with hypersensitivity or contraindications to remifentanil, dexmedetomidine, or lidocaine.

Design outcomes

Primary

Measure	Time frame
Incidence of urinary catheter-related bladder discomfort	—

Secondary

Measure	Time frame
incidence of emergence delirium, analgesic requirement, incidence of postoperative nausea and vomiting	—

Countries

Korea, Republic of

Contacts

Public ContactAram Doo

Jeonbuk National University Hospital

ruiwin3518@gmail.com+82-63-250-1249

Outcome results