None listed
Conditions
Interventions
Dietary Supplement : * Among natural substances known to have anti-Helicobacter activity, curcumin and mastic gum are reported to have significantly enhanced antibacterial activity when enclosed in ph
Sponsors
Gachon University Gil Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients aged 20 years or older who are on outpatient follow-up in Gachon University Gil Medical Center
Exclusion criteria
Exclusion criteria: Subjects with any of the following will not be included in the study: 1) Received anticancer therapy within 6 months. 2) Chronic hepatitis or cirrhosis of the liver 3) Uncontrolled hypertension (systolic >150 mmHg and/or diastolic >100 mmHg) or clinically significant (i.e., active) cardiovascular disease: e.g., cerebrovascular accident (within 6 months), myocardial infarction (within 6 months), unstable angina, New York Heart Association Grade II or greater congestive heart failure, or significant cardiac arrhythmia that is not controlled by medication or that could potentially interfere with treatment. 4) History or evidence of congenital bleeding diathesis or coagulopathy with bleeding risk. 5) Any thrombus, embolus within 6 months 6) Major or unhealed wounds, or incompletely healed fractures. 7) Active gastrointestinal bleeding, peptic ulcer. 8) History of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 6 months. 9) Pregnant or lactating women. 10) Known hypersensitivity to urea. 11) Diagnosed with phenylketonuria. 12) Have asthma, pneumonia, chronic obstructive pulmonary disease, or other pulmonary disease. 13) Has undergone gastric subtotal resection, gastric anterior resection 14) History of taking PPIs, antibiotics within 2 weeks prior to dosing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in delta value measured in the urea breath test (before and after taking helicurmin) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate digestive system-related symptoms and changes | — |
Countries
Korea, Republic of
Contacts
Public ContactJi-Hyeon Park
Gachon University Gil Medical Center
Outcome results
None listed