None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Among the patients requiring gastro-duodenal endoscopy, endoscopic ultrasound, or endoscopic retrograde biliary pancreatic angiography for medical purposes, the pancreatic cancer group should meet the criteria numbered 1, 2, and either 3 or 4. The control non-pancreatic cancer group should meet the criteria numbered 1, 2, and either 5 or 6. 1. Be at least 19 years old 2. Have completed the informed consent for planned upper endoscopy, endoscopic ultrasound, or endoscopic retrograde cholangiopancreatography before the duodenal fluid collection. 3. A biopsy with proven stage I-IV pancreatic ductal adenocarcinoma (PDAC). 4. Suspected pancreatic cancer on imaging and scheduled for an endoscopic ultrasound-guided pancreatic biopsy. 5. Patient with pancreatic cystic tumors or patients with acute or chronic pancreatitis 6. No evidence of a pancreatic disease
Exclusion criteria
Exclusion criteria: The exclusion criteria for the pancreatic cancer and the control non-pancreatic cancer groups will be: 1. Innate or post-surgical anatomy that precludes direct sampling of duodenal fluid. 2. Hemodynamically unstable and unable to have an endoscopy performed. 3. A large amount of ascites fluid that is not controlled and unable to have an endoscopy performed. 4. A coagulation disorder that cannot be corrected and unable to have an endoscopy performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Primary Objective: Adequacy of the amount of duodenal fluid collected (approximately 1.5 mL);2. Secondary objective: Qualitative assessment of the exosomes form the collected duodenal fluids (microRNA) | — |
Countries
Korea, Republic of
Contacts
Public ContactEUN HA KIM
Asan Medical Center
Outcome results
None listed