None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A. Aged 40-60 B. Patients scheduled for general anesthesia in the operating room of Kyungpook National University Hospital C. American Society of Anesthesiologists (ASA) physical status classification of 1-2
Exclusion criteria
Exclusion criteria: A. Emergency surgery B. Patients with a neurological or psychiatric history C. Patients who have taken central nervous system active drugs within 1 month prior to surgery D. Patients with allergies to drugs used in the study (benzodiazepines, opioids) E. Patients who do not wish to participate in the study F. Patients with aspartate aminotransferase/alanine aminotransferase levels more than twice the normal value within one week prior to surgery G. Patients with a total bilirubin level of 3.0mg/dL or higher within one week prior to surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the EEG transformation index of approximate entropy | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in PSI | — |
Countries
Korea, Republic of
Contacts
Kyungpook National University Hospital