Association of Remifentanil Dose with Nociceptive Index and Postoperative Pain in Patients Under General Anesthesia

Comparison of Analgesia Nociception Index (ANI) and Postoperative Pain Change followed by Remifentanil Dose in General Anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0009597

Enrollment

Registered

2024-07-05

Start date

2024-09-23

Completion date

Unknown

Last updated

2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The study compares two groups receiving remifentanil via the Target Controlled Infusion (TCI) method at concentrations of 10 ng/mL and 3 ng/mL, with the infusion duration and method being the s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients undergoing laparoscopic cholecystectomy under general anesthesia

Exclusion criteria

Exclusion criteria: 1. history of drug abuse 2. other surgeries are being conducted simultaneously 3. severe liver disease 4. urgent or emergent case 5. QT prolongation in preoperative electrocardiography 6. any cardiovascular or respiratory disease 7. renal disease 8. current medication use 9. previous abdominal surgery

Design outcomes

Primary

Measure	Time frame
Postoperative pain	—

Secondary

Measure	Time frame
ANI value	—

Countries

Korea, Republic of

Contacts

Public ContactSeung-wan Hong

Konkuk University Medical Center

20150077@kuh.ac.kr+82-2-2030-5448

Outcome results