The effect of opioid-free anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0009593

Enrollment

150

Registered

2024-07-05

Start date

2024-07-01

Completion date

Unknown

Last updated

2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Different drugs are used for preventing nociception during surgery, according to the allocated group. Opioid-free anesthesia group (Experimental group): Before induction of anesthesia, dexmede

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing elective laparoscopic cholecystectomy under general anesthesia Patients with American Society of Anesthesiologists physical status (ASA PS) 1-3

Exclusion criteria

Exclusion criteria: 1) severe bradycardia (heart rates < 45 bpm), sick sinus syndrome, 2nd or 3rd degree atrioventricular block 2) severe heparorenal dysfunction 3) ASA PS 4 or above 4) coagulation abnormality 5) allergic history to local anesthetics

Design outcomes

Primary

Measure	Time frame
incidence of postoperative nausea and vomiting	—

Secondary

Measure	Time frame
pain intensity	—

Countries

Korea, Republic of

Contacts

Public ContactAram Doo

Jeonbuk National University Hospital

ruiwin3518@gmail.com+82-63-250-1249

Outcome results