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The impact of remimazolam and propofol on perioperative hypothermia during lung surgery

The impact of remimazolam versus propofol on perioperative hypothermia during video-assisted thoracoscopic surgery: a prospective randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0009497
Enrollment
146
Registered
2024-06-03
Start date
2025-03-30
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : - Infusion of remimazolam for the induction of anesthesia - 6~12 mg/kg/hr - Terminated at loss of consciousness - Infusion of propofol for the induction of anesthesia - Less than 55 years of

Sponsors

The Catholic University of Korea, Seoul St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patient scheduled for video-assisted thoracoscopic lobectomy or segmentectomy 2. ASA physical status I or II 3. Patient or legal representative voluntarily decides to participate in this clinical study and signs and seals the subject's written consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Patient scheduled for emergency surgery 2. Patient who cannot communicate 3. Patient who is pregnant or nursing 4. BMI more than or equal to 35 kg/m^2 5. Body temperature less than 36.0 ºC or more than 37.5 ºC 6. Patient with infectious disease 7. Contraindication to remimazolam 8. Contraindication to propofol 9. Allergy or history of adverse event to any drugs used in the study

Design outcomes

Primary

MeasureTime frame
Intraoperative hypothermia

Secondary

MeasureTime frame
Intraoperative mean body temperature;Hypothermia within 1 hour from induction;Mean body temperature within 1 hour from induction;Hypothermia in post-anesthesia care unit;Postoperative shivering;Postoperative shivering grade;Postoperative thermal comfort

Countries

Korea, Republic of

Contacts

Public ContactHoon Choi

The Catholic University of Korea, Seoul St. Mary's Hospital

hoonie83@naver.com+82-2-2258-2236

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Mar 20, 2026