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Response Surface Modeling Between Remimazolam and Sevoflurane: Minto and Greco Model Comparison.

Surface Modeling of the Response Between Remimazolam and Sevoflurane: Minto and Greco Model Comparison.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0009423
Enrollment
30
Registered
2024-05-10
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subjects (15 males, 15 females) scheduled to undergo surgery under general anesthesia in the central operating room at our institute. Subjects in the American Society of Anesthesiologists physical status classification 1 or 2 Subjects who voluntarily agreed in writing to participate in this study

Exclusion criteria

Exclusion criteria: Subjects who are allergic to remimazolam or sevoflurane. Subjects without renal, hepatic, neuromuscular, or neurologic disease and taking medications related to these Subjects who are habitually taking psychoactive drugs or have ischemic heart disease. Pregnant women

Design outcomes

Primary

MeasureTime frame
Relationship between sevoflurane and remimazolam (synergistic, additive, infra-additive)—

Secondary

MeasureTime frame
BIS values for each drug's Ce combination—

Countries

Korea, Republic of

Contacts

Public ContactYeong-min Yoo

Pusan National University Yangsan Hospital

rym721@naver.com+82-55-360-2129

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026