None listed
Conditions
Interventions
Drug : For CV1 (Jin Kyungokgo) group, take 1 pack (22.5 g) twice a day for adults before or between meals (between meals).
Sponsors
Korea Institute of Oriental Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Those aged 19 years or older and at least 12 weeks have passed since being diagnosed with COVID-19 -Those who has continuously experienced fatigue for 4 more than weeks that they did not experience before being diagnosed with COVID-19. -Those who scored 36 or more Fatigue Severity Scale (FSS) score. -Participants do not have any problems with overall cognitive function and voluntarily agreed to participate in the study through written consent
Exclusion criteria
Exclusion criteria: -Those with a past or current history of organic diseases that can cause fatigue (cancer, sleep disorders, chronic hepatitis, cirrhosis, chronic renal failure, tuberculosis, asthma, multiple sclerosis) -Those with diseases that may affect the taking or absorption of drugs (dysphagia, clinically serious digestive disorders, galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption) -Those with uncontrolled diabetes -Those with a history of allergy to clinical research drugs (Kyungokgo) -Those with a history of liver disease or kidney disease, or if AST, ALT, BUN, and Creatinine exceed three times the upper limit of normal on a blood test. -Women who are pregnant, may become pregnant, or are lactating -Participating in another study within 30 days prior to participating in a clinical study -When the researcher determines that participation in the study is difficult due to clinically significant psychiatric symptoms, medical disease, laboratory findings, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue Severity Scale (FSS) scores after herbal medicine administration for up to 12 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Final medication adherence;Fatigue Severity Scale (FSS) scores ;ChFS(Chalder Fatigue Scale) score and subscale score;EQ-5D-5L score;PSQI-K (Korean version of Pittsburgh Sleep Quality Index) Global score;K-MOCA(Korean-Montreal cognitive assessment) score;BDI (Becks’ depression inventory) score;DF(digit forward) score, DB(digit backward) score, DF-DB score;Computerized neurocognitive function test score;Short Physical Performance Battery (SPPB);Analysis of target recruitment rate, dropout rate, and dropout reason for feasibility evaluation;Final treatment success rate | — |
Countries
Korea, Republic of
Contacts
Public ContactChan-Young Kwon
Dong-eui University
Outcome results
None listed