None listed
Conditions
Interventions
Drug : Transcranial motor evoked potentials are conducted to record baseline amplitude and latency from the bilateral anterior tibialis, abductor hallucis, and abductor pollicis brevis muscles. Concur
Sponsors
Seoul National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: During spine surgery, transcranial motor evoked potentials are measured in adult patients over 18 years of age with normal preoperative muscle strength in both upper and lower extremities.
Exclusion criteria
Exclusion criteria: Patients who do not consent to the study, do not undergo invasive arterial pressure monitoring during surgery, do not have additional venous catheter insertion during surgery, and whose first arterial blood test during surgery shows an ionized calcium concentration of 1.15 mmol/L or higher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ratio of the maximum amplitude among the three amplitudes measured at the same site 1, 3, and 5 minutes after the injection of calcium chloride to the initial amplitude based on the amplitude of the transcranial motor evoked potentials measured in the left tibialis anterior muscle before the injection of calcium chloride | — |
Secondary
| Measure | Time frame |
|---|---|
| mean arterial blood pressure, pulse rate, peripheral oxygen saturation, bispectral index, body temperature;arterial blood gas analysis;Stimuli used for motor evoked potential and somatosensory evoked potential tests;Amplitude and latency measured in the anterior tibial muscle, abductor hallucis, and abductor pollicis brevis during the motor evoked potential test;Amplitude and latency measured at the frontal pole zero, central zero, and C3'/C4' during the somatosensory evoked potential test | — |
Countries
Korea, Republic of
Contacts
Public ContactWoo-young Jo
Seoul National University Hospital
Outcome results
None listed