None listed
Conditions
Interventions
Procedure/Surgery : For prostate cancer screening at the health examination center, men who underwent serum PSA testing and showed PSA elevation (3-10 ng/mL) will be selected. They will then be random
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: ? Men aged 50-69 who visit the health examination center and desire prostate cancer screening. ? Serum PSA level ranging from 3-10 ng/mL. ? Normal findings on digital rectal examination. ? Patients who have not previously undergone prostate tissue biopsy. ? Patients who do not have contraindications for prostate MRI. ? Patients who are able to voluntarily provide informed consent.
Exclusion criteria
Exclusion criteria: ? Patients with a history of prostate tissue biopsy within the past 3 years. ? Patients with pacemaker insertion, claustrophobia, or eGFR below 45 ? Patients with total hip joint replacement or those with metallic materials in the pelvis. ? Patients who have undergone transurethral prostatectomy. ? Patients who have undergone surgery for benign prostatic hyperplasia or prostate cancer. ? Patients who have taken 5-alpha reductase inhibitors within the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of clinically insignificant prostate cancer | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection rate of clinically significant prostate cancer;Number of total biopsy cores;Number of patients requiring prostate biopsy | — |
Countries
Korea, Republic of
Contacts
Public ContactKye Jin Park
Asan Medical Center
Outcome results
None listed