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The effect of intraoperative remifentanil and sufentanil TCI on postoperative pain and postoperative opioid consumption in breast cancer surgery: A randomized controlled study

The effect of intraoperative remifentanil and sufentanil TCI on postoperative pain and postoperative opioid consumption in breast cancer surgery: A randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0009226
Enrollment
86
Registered
2024-03-07
Start date
2024-02-27
Completion date
Unknown
Last updated
2025-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Experimental Group, Sufentanil Group (Group S): Prepare Sufentanil 50 mcg/cc by diluting it in normal saline 49 cc to achieve a concentration of 1 mcg/cc, totaling 50 cc in a syringe. Administe

Sponsors

Chung-Ang University Gwangmyeong Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult female patient with American Society of Anesthesiologists physical status level 1-2 scheduled for breast-conserving surgery under general anesthesia

Exclusion criteria

Exclusion criteria: - Under 18 years of age or over 70 years of age - ASA 3 or higher - BMI 35 or higher - Pregnant and lactating women - Patients with serious cardiovascular, liver, kidney, and hematological abnormalities - Patients with uncontrolled respiratory disease and moderate to severe pulmonary dysfunction - Those taking opioids, anticonvulsants, or antidepressants - Those with a history of hypersensitivity or serious side effects to drugs related to this study (opioids, acetaminophen, tramadol) - During the surgical procedure, the scope of surgery is reduced to a tumor resection or expanded to a total mastectomy. - Those who refused to participate in this study

Design outcomes

Primary

MeasureTime frame
Opioid consumption during 24 hours after surgery

Secondary

MeasureTime frame
Pain score (11-point NRS) at 30 minutes, 6 hours, 24 hours, and 48 hours after surgery, presence of nausea and vomiting, number of antiemetic drugs administered after surgery

Countries

Korea, Republic of

Contacts

Public Contactmin kyoung kim

Chung-Ang University

ddolpaki86@naver.com+82-2-2222-1524

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026