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Safety investigation of Fexuprazan, a gastric acid secretion inhibitor, in patients with cirrhosis

Safety investigation of Fexuprazan, a gastric acid secretion inhibitor, in patients with cirrhosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0009189
Enrollment
99
Registered
2024-02-21
Start date
2024-01-15
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Soonchunhyang University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Test group: ? Liver cirrhosis patients between 20 and 75 years old ?Milan gastroesophageal reflux requiring endoscopic drug treatment within the last 6 months Patients with liver cirrhosis who have been diagnosed with the disease Control group: ? Patients with no evidence of disease between the ages of 20 and 75 ?Patients with no evidence of liver disease in blood tests or imaging tests ? Milan gastroesophageal reflux disease was diagnosed by endoscopy within the last 6 months. Patients who took P-CAB

Exclusion criteria

Exclusion criteria: 1. Patients with non-targeted liver cirrhosis who have variceal hemorrhage, hepatic encephalopathy, Gansin syndrome, or spontaneous peritonitis 2. Patients who have experienced side effects after previously using Proton Pump Inhibitor 3.Patients with untreated malignant tumor 4. Pregnant patients 5. Patients who did not consent to participate in the study 6. If you have taken fexuprazan at least 6 months prior to the time of Inclusion

Design outcomes

Primary

MeasureTime frame
Changes in liver values (AST or ALT) due to taking P-CAB

Secondary

MeasureTime frame
Occurrence of spontaneous bacterial peritonitis

Countries

Korea, Republic of

Contacts

Public ContactSang gyune Kim

Soon Chun Hyang University Hospital Bucheon

ksgyune@gmail.com+82-32-621-5079

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026