The Effects of Whey Protein Supplementation on Hepatic Function in Patients with Non-Alcoholic Fatty Liver Disease after Short-term Resistance Exercise Training

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0009143

Enrollment

Registered

2024-01-30

Start date

2024-06-03

Completion date

Unknown

Last updated

2024-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement, Others : (1) Dietary Methods (1)-1 Meal Intake: All study participants will undergo resting metabolic rate testing using a respiratory gas analyzer before the intervention to deter

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Individuals who understand the purpose of this study and voluntarily provide written consent to participate in the research. -Individuals with a body mass index (BMI) of 23.0 kg/m² or higher. -Men and women aged 20 to 60 diagnosed with NAFLD according to the Asia-Pacific NAFLD diagnostic guidelines. -Men and women aged 20 to 60 diagnosed with MASLD (metabolic-associated steatotic liver disease) and METald according to the new nomenclature guidelines for NAFLD. -Individuals with no weight change in the past three months. -Individuals with no exercise experience in the past three months (defined as less than once a week and less than 30 minutes per session). -Individuals who are eligible for exercise participation according to the Physical Activity Readiness Questionnaire (PAR-Q+). -Individuals without health issues that would prevent them from engaging in exercise. -Individuals with metabolic syndrome who are deemed fit for exercise under a physician's discretion.

Exclusion criteria

Exclusion criteria: -Individuals with heart or kidney diseases. -Individuals taking medications that may affect research outcomes (such as those for hypertension or diabetes). -Smokers. -Individuals with allergies to milk and dairy products or lactose intolerance. -Students and researchers affiliated with the investigator's laboratory. -Individuals with glaucoma, cataracts, or infectious ocular diseases. -Pregnant or breastfeeding individuals.

Design outcomes

Primary

Measure	Time frame
Hepatic fat content;Blood marker (liver function marker, lipid profile, lipid metabolism, carbohydrate metabolism, NAFLD marker, inflammation marker etc.)	—

Secondary

Measure	Time frame
Body composition;Liver ultrasound image;Isokinetic muscular function;Hand grip;Blood pressure;Resting metabolic rate;1 repetition maximum, 1-RM;Questionnaire (Sleep quality, health-related quality of life, physical activity, depression);Nutrient intake	—

Countries

Korea, Republic of

Contacts

Public ContactChaebeen Kim

Pusan National University

chaebeen@pusan.ac.kr+82-51-510-2713

Outcome results