Comparison of differences in hemodynamic changes according to general anesthesia induction dose of remimazolam based on total weight and lean weight in obese patients

Comparison of differences in hemodynamic changes according to general anesthesia induction doses of remimazolam (byfavoju) based on total body weight and lean body mass in patients with a body mass index of 30 or more: a multicenter clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0009080

Enrollment

168

Registered

2023-12-28

Start date

2024-02-05

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the case of anesthesia induction with remimazolam in patients with a body mass index of 30 or higher who are scheduled for general anesthesia, there is a difference between the intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients over 19 with a body mass index of 30 and above who are scheduled to undergo tracheal intubation and general anesthesia

Exclusion criteria

Exclusion criteria: a) Preoperative medications include antidepressants, anti-epidemic, narcotic painkillers, and antiemetic medications b) Patients with ASA-PS 4 or higher c) c) benzodiazepines flumazenil hypersensitivity d) a patient's refusal e) If the average arterial pressure is more than 110mmHg and the heart rate is more than 120 times per minute by taking the average blood pressure and heart rate measured in the ward as baseline values f) a patient unable to measure blood pressure in the upper extremity g) Patients with the same arm with a blood pressure gauge and intravenous route due to surgery or underlying disease h) Measures to protect vulnerable persons: Vulnerable subjects (minors, pregnant women, inmates, elderly, hospital staff or medical school, nursing students, pharmaceutical company employees, terminally ill patients, mentally retarded persons and persons with disabilities who cannot express their intentions) are not included in the study.

Design outcomes

Secondary

Measure	Time frame
Time from drug administration to unconsciousness	—

Primary

Measure	Time frame
Blood pressure after tracheal intubation	—

Countries

Korea, Republic of

Contacts

Public ContactYoung Suk Kwon

Hallym University Medical Center- Chuncheon

gettys@hallym.or.kr@gettys@hallym.or.kr+82-33-240-5000

Outcome results