None listed
Conditions
Interventions
Dietary Supplement : Subjects will be randomly allocated to placebo or experimental group and take 4 tablets once a day for 8 weeks.
Sponsors
Gachon University Gil Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subject who agrees to participate in the study and signs the informed consent form 2) 40–74 years old 3) persistent respiratory symptoms including cough and sputum more than 3 months
Exclusion criteria
Exclusion criteria: 1) abnormal FEV1/FVC 2) respiratory diseases including tuberculous-destroyed lung, bronchiectasis, acute bronchitis, chronic bronchitis, asthma, COPD, lung cancer, pneumonia, tuberculosis, acute upper respiratory infections, diabetes, cardiovascular diseases, GERD 3) taking pills or extracts of quince or deodeok within recent 2 weeks persistently 4) taking antioxidants or anti-inflammatory drugs or dietary supplements within recent 6 weeks 5) serum creatinine = 2 mg/dL or ESRD 6) total bilirubin = 2 mg/dL, AST or ALT = 1.5 x normal value 7) uncontrolled psychologic disease or alcoholics 8) smoker 9) BMI = 35kg/m2 10) history of hypersensitivity for testing substance or severe food allergy 11) involving other clinical trials within 1month 12) pregnant or lactating, or planning to become pregnant 13) the investigator's decision
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory symptoms;FeNO;spirometry | — |
Secondary
| Measure | Time frame |
|---|---|
| safety markers | — |
Countries
Korea, Republic of
Contacts
Public ContactHuiyeong Hwang
Gachon University Gil Medical Center
Outcome results
None listed