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Efficacy and Safety of 1L Polyethylene Glycol plus Low-dose Ascorbic Acid Compared to D-Sorbitol and Picosulfate plus Ascorbic Acid

Efficacy and Safety of 1L Polyethylene Glycol plus Low-dose Ascorbic Acid Compared to D-Sorbitol and Picosulfate plus Ascorbic Acid: Multi-center, randomized, single-blind prospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0009000
Enrollment
200
Registered
2023-11-30
Start date
2023-12-01
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the Gastroenterology outpatient departments of Chung-Ang University Hospital and Chung-Ang University Gwangmyeong Hospital, for patients aged 19 years and above who are prescribed colonoscop

Sponsors

Chung-Ang Univerisity Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The following are the inclusion criteria for patients eligible to participate in the study: Adult men and women aged 19 years and above. Patients scheduled to undergo colonoscopy for screening or diagnostic purposes at the Gastroenterology outpatient departments of Chung-Ang University Hospital and Chung-Ang University Gwangmyeong Hospital from the start of the study. Patients who have provided informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: The following are the criteria for excluding patients from participating in the study: 1. Patients with functional or anatomical gastrointestinal obstructions (such as gastric paresis, pyloric stenosis, functional bowel obstructions, toxic megacolon, etc.), active gastrointestinal bleeding, or intestinal perforation. 2. Patients with dehydration, severe vomiting, or severe diarrhea. 3. Patients with a history of or current inflammatory bowel disease (Crohn's disease or ulcerative colitis) or those strongly suspected of having such conditions. 4. Patients with confirmed gastric ulcers. 5. Patients with a known history of intestinal adhesions that require surgery, or those in an acute abdominal condition requiring surgical intervention. 6. Patients with a history of previous gastrointestinal resection surgery (excluding appendectomy). 7. Patients with a history of glucose-6-phosphate dehydrogenase deficiency. 8. Patients with significant cardiovascular diseases (New York Heart Association classification III and IV), respiratory diseases, kidney disease (creatinine clearance <30mL/min), liver disease, or a combination of these conditions. 9. Patients with dementia, cognitive impairment, or altered consciousness. 10. Patients with a history of cardiac arrest. 11. Patients with known hypersensitivity or allergic reactions to the medications used. 12. Pregnant and lactating women. 13. Patients who do not provide informed consent for the study. 14. Other patients deemed unsuitable for the study by the principal investigator or study personnel.

Design outcomes

Primary

MeasureTime frame
Proper bowel preparation status among groups

Secondary

MeasureTime frame
Cecal intubation time, withdrawal time, polyp detection rate, adenoma detection rate, safety of bowel preparation agents, tolerability, compliance, satisfaction

Countries

Korea, Republic of

Contacts

Public ContactKyuwon Kim

Chung-Ang Univerisity Hospital

kkw417@naver.com+82-2-6299-0000

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026