None listed
Conditions
Interventions
Drug : - 30mg, 60mg, 120mg of single-drug kanasartan and
- Prescribed using various step-by-step medications of compounded ducarb (Fimasartan + Amlodipine) 30/5mg, 60/5mg, 30/10mg, 60/10mg
It is presc
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - 18-80-year-old patient - ABPM average systolic blood pressure greater than 140 mmHg or diastolic blood pressure greater than 90 mmHg
Exclusion criteria
Exclusion criteria: - Those who refused to participate in this study - Patients with blood pressure >180/110mmHg or hypertension emergency - Patients with heart failure with a left ventricular ejection fraction of 40% or less on echocardiography - Chinese characters with a history of taking antihypertensive drugs within a month - a drug allergy - a patient diagnosed with secondary hypertension - Cardiovascular diseases such as cerebral aneurysm and aortic disease, or a history of stroke in the last year - a pregnant woman of childbearing age - end-stage renal failure - Less than 2 years of survival - Drug allergy corresponding to kanab and ducarb components
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average daily systolic blood pressure on ABPM at 4-week follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Average daily diastolic blood pressure on ABPM at 4-week follow-up;Average weekly systolic and diastolic blood pressure at 4-week follow-up;Average night systolic and diastolic blood pressure at 4-week follow-up;Target blood pressure reading achieved at 4-week follow-up;Changes in daily blood pressure variability at 4-week follow-up (coefficient of variation, standard deviation) | — |
Countries
Korea, Republic of
Contacts
Public ContactLee jieun
Asan Medical Center
Outcome results
None listed