None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -Adult men and women over 50 years of age -Able to walk independently - Those who understand the explanation of this study and agree to participate
Exclusion criteria
Exclusion criteria: ? People with neurological diseases that affect walking (e.g., traumatic brain injury (TBI), stroke, multiple sclerosis) ? Those who have undergone orthopedic surgery within the last 6 months or have had a central fracture (central bone: spine, pelvis, lower extremity) within 1 year ? Liver level (more than 3 times the upper normal limit) ? Those with abnormalities in kidney function (eGFR 1.2) ? Chronic disease patients (a) Type 1 diabetes or uncontrolled type 2 diabetes (fasting blood sugar = 160mg/dl), (b) Uncontrolled hypertension (>160/100 mmHg), (c) heart failure (NYHA class 3,4), (d) chronic obstructive pulmonary disease (COPD, grade C, D), (e) Those with liver cirrhosis (Child-Pugh B, C) ? Those who have been diagnosed with cancer requiring treatment within the last 5 years ? Those who are unable to measure grip strength and lower extremity strength ? Persons with cognitive decline to the point where they cannot follow instructions ? Any other person who is unable to participate in the study at the discretion of the PI (principal investigator)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal Muscle Index (SMI) | — |
Secondary
| Measure | Time frame |
|---|---|
| gait speed ;five times sit to stand test (FTST);Timed up and go (TUG);Low extremity muscle strength;MVC amplitude of Quadriceps muscle surface EMG ;Korean version of SARC-F ;Korean version of Patient Health Questionnaire-9(PHQ-9);Korean version of EuroQol-5 Dimension(EQ-5D-5L);Korean Version of Montreal Cognitive Assessment (MoCA-K);coding of Koren Wechsler Adult Intelligence Scale-4 evaluation items(K-WAIS-4; coding) ;Cogscreen, EmoCog® (Smartphone App embedded cognitive function assessent tool);hand grip strength;step length ;Double limb support time ;PDT, EmoCog® (Smartphone App. embedded neurodegenerative disease screening tool) | — |
Countries
Korea, Republic of
Contacts
Keimyung University Dongsan Hospital