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Cognitive and mood effects of home-based, remotely supervised strength exercise combined with guideline-based aerobic physical activity modification in Parkinson’s Disease: a randomized controlled trial

Cognitive and mood effects of home-based, remotely supervised strength exercise combined with guideline-based aerobic physical activity modification in Parkinson’s Disease: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008864
Enrollment
64
Registered
2023-10-12
Start date
2023-10-13
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : 1. Home-based and remotely supervised strength exercise programs 1) Exercise location: Incheon university sports center (for initial face-to-face training during 4 weeks) and participan

Sponsors

Inha University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients who were diagnosed with Parkinson's disease based on the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria 2) Patients who were aged between 50 and 80 3) Patients with Hoehn and Yahr stage 3 or less 4) Patients who did less than the recommended aerobic exercise proposed by the American College of Sports Medicine (ACSM) (ex.vigorous exercise done <75 minutes a week or moderate exercise done <150 minutes a week) 5) Patients who were on stable dopaminergic pharmacotherapy over more than 3 months

Exclusion criteria

Exclusion criteria: 1) Patients with neurological, orthopedic, or cardiac comorbidities that make them unfit to do exercise 2) Patients who were unable to complete questionnaires due to cognitive impairment (MoCA-K<18) 3) Patients on antipsychotics 4) Patients who have symptoms or signs suggesting atypical or secondary parkinsonism (ex. cerebellar signs, supranuclear gaze palsy, apraxia, prominent autonomic failure, or other cortical signs; multiple strokes with stepwise progression of symptoms) 5) Patients who were unavailable for more than 10% of the study period

Design outcomes

Primary

MeasureTime frame
Change in scores of the Korean Dementia Rating Scale-2

Secondary

MeasureTime frame
Change in scores of the Apathy Scale;Change in scores of the MDS-UPDRS part 3 ;Change in scores of the Beck Depression Inventory;Change in scores of the Beck Anxiety Inventory;Change in scores of the Pittsburgh Sleep Quality Index

Countries

Korea, Republic of

Contacts

Public ContactRyul Kim

Inha University Hospital

arkrk86@inha.ac.kr+82-32-890-3764

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: May 30, 2026