None listed
Conditions
Interventions
Dietary Supplement : • Fermented soybean TCD23-5(high content of effective microorganisms, Doenjang powder): twice a day, 1 pack once, after breakfast/dinner(6 g/day, 6 g/day for fermented soybean)
•
Sponsors
Jeonbuk National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adult men and women aged 19 years or older and 75 years old or younger at the screening test. 2) Subjects with an LDL-cholesterol of 130 mg/dL or more or a total cholesterol of 200 mg/dL or more in a fasting blood test at the screening test.
Exclusion criteria
Exclusion criteria: 1) Those with clinically significant acute or chronic cardiocerebrovascular, endocrine, immune, respiratory, hepatobiliary, renal and urinary, neuropsychiatric, musculoskeletal, inflammatory and hematologic neoplastic, gastrointestinal, systemic and infectious diseases requiring treatment. 2) Those who have taken medicines and health functional foods related to improving intestinal flora and cholesterol within 1 month before screening 3) Those who are taking diabetes medications at the screening test. 4) Patients with uncontrolled hypertension at the screening test. 5) Those who have received antipsychotic drug treatment within 3 months prior to screening test. 6) Those with or suspected of alcoholism or drug abuse 7) pregnant or lactating women 8) Women of childbearing potential who do not accept the practice of adequate contraception 9) Those who participated in other human application tests within 3 months prior to screening test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of intestinal microbiome;lipid metabolism index | — |
Secondary
| Measure | Time frame |
|---|---|
| lipid metabolism index;Atherogenic index;inflammatory markers;Short chain fatty acids | — |
Countries
Korea, Republic of
Contacts
Public ContactHui-yeon Jang
Jeonbuk National University Hospital
Outcome results
None listed