High-flow nasal cannula oxygen therapy in high-risk patients under regional anesthesia and sedation

High-flow nasal cannula oxygen therapy during regional anesthesia under propofol sedation in patients at risk of hypoxemia: a randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008859

Enrollment

112

Registered

2023-10-11

Start date

2023-11-07

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : * High-flow nasal cannula - Oxygen was administered at 40-60·min-1, FiO2 1.0 via an HFNO system - OptiflowTM

Fisher & Paykel Healthcare, New Zealand *Standard oxygen therapy - 100% oxygen 6L/min simple mask nasal cannula

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: * Patients with ASA physical status 3-4 or elderly patients over 70 years of age * Patients scheduled for surgery under propofol sedation after regional anesthesia

Exclusion criteria

Exclusion criteria: * Those who are contraindicated for brachial plexus block or spinal anesthesia * Those who are allergic to propofol * Patients scheduled for tracheal intubation or who underwent tracheostomy *Patients who are presently undergoing oxygen therapy. * A person who refuses to give consent or who is judged unfit to participate in the study by medical staff for other reasons

Design outcomes

Primary

Measure	Time frame
Number of patients with hypoxia event (oxygen saturation less than 95%)	—

Secondary

Measure	Time frame
Number of occurrences of hypoxia events (oxygen saturation less than 95%);Lowest oxygen saturation ;Propofol dosage;Surgeon's satisfaction;Number of airway interventions (chin lift, jaw thrust, oral airway, mask ventilation, intubation);Adverse event rate;Arterial blood oxygen partial pressure (PaO2) analyzed by arterial blood gas analysis;Regional Hb oxygen saturation index (rSO2) through cerebral oximetry;oxygen reserve index (ORI)	—

Measure

Time frame

Number of occurrences of hypoxia events (oxygen saturation less than 95%);Lowest oxygen saturation ;Propofol dosage;Surgeon's satisfaction;Number of airway interventions (chin lift, jaw thrust, oral airway, mask ventilation, intubation);Adverse event rate;Arterial blood oxygen partial pressure (PaO2) analyzed by arterial blood gas analysis;Regional Hb oxygen saturation index (rSO2) through cerebral oximetry;oxygen reserve index (ORI)

—

Countries

Korea, Republic of

Contacts

Public ContactYeon Ju Kim

Asan Medical Center

clever8808@naver.com+82-2-3010-3888

Outcome results