None listed
Conditions
Interventions
Dietary Supplement : • Perilla frutescens extract group: Once a day, 2 capsule once for 12 weeks
• Placebo group: Once a day, 2 capsule once for 12 weeks
Sponsors
SFCBIO
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age 55 or older at the screening examination and able to communicate smoothly (2) KMMSE~2 of 25-28 (3) Participants who have fully understand the information provide d about the study voluntarily decided to participate and agree to comply with precautions
Exclusion criteria
Exclusion criteria: (1) subjects are now receiving treatment due to SCID (structured clinical interview of DSM-IV) axis I disorder during the screening period, or have a history of treatment within 3 years (2) body mass index (BMI) 2.0 mg/dl (10) pregnant or lactating women (11) Women of childbearing age who did not use the proper methods of contraception (12) A person who is judged unsuitable for participation in the study by the director of the study due to other reasons, including diagnostic test results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADAS-cog total score;Korean Mini-Mental Status Examination~2 (K-MMSE~2) | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain-Derived Neurotrophic Factor(BDNF);Amyloid ß | — |
Countries
Korea, Republic of
Contacts
Public ContactJongcheon Joo
Wonkwang University Oriental Medical Hospital, Jeonju
Outcome results
None listed