None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults aged between 18-85 Diagnosed with persistent atrial fibrillation lasting for more than 7 days, as confirmed by a 12-lead ECG, Holter monitor, event recorder, or exercise stress test Patients who have been diagnosed with atrial fibrillation for more than 3 years but less than 10 years Resistant to or having side effects from one or more class I or III antiarrhythmic drugs Patients receiving their first (de-novo) catheter ablation procedure for atrial fibrillation
Exclusion criteria
Exclusion criteria: Refusal to participate in the research BMI = 35kg/m^2 Intracardiac thrombus Contraindications to anticoagulant therapy History of surgical or interventional treatment for atrial fibrillation Severe valvular heart disease, aortic stenosis, or mechanical prosthetic valve Anteroposterior diameter of the left atrium of 60mm or more NYHA class IV heart failure Thoracic surgery within the last 3 months Planned thoracic surgery within the next 3 months End-stage heart failure or severe renal failure (estimated glomerular filtration rate [MDRD method] < 30mL/min/1.73m) Pregnant or breastfeeding women Acute coronary syndrome within the last 3 months Dementia Co-morbidity (such as ongoing cancer treatment) with expected survival of less than 1 year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence rate of atrial tachyarrhythmia (including atrial fibrillation, atrial flutter, and atrial tachycardia) lasting for more than 30 seconds after the 3-month blanking period following the initial procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence rate of all types of atrial arrhythmias, including atrial fibrillation, atrial tachycardia, or atrial flutter, each lasting more than 30 seconds and confirmed by ECG, occurring within 1 year after the 3-month blanking period post-procedure, regardless of medication use;All types of atrial arrhythmia events occurring during the 3-month blanking period after the procedure;Total procedure time (min), total radiation time (min);Success rates of pulmonary vein isolation or each linear ablation;The proportion maintaining sinus rhythm at 6 months and 12 months follow-up;Complications related to the procedure (stroke, pericardial effusion, pulmonary vein stenosis, esophageal injury, death) ;Occurrence of bradyarrhythmic events causing hemodynamic issues and the need for pacemaker insertion;Whether re-intervention or surgery was required | — |
Countries
Korea, Republic of
Contacts
Public ContactMyung-Jin Cha
Asan Medical Center
Outcome results
None listed