None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patient who received open heart surgery in Department of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center 2) Adult aged 19 years or above 3) Patient who received heart surgery using cardiopulmonary bypass 4) Voluntarily signed and dated written informed consent after sufficient explanation about the full nature and purpose of the study 5) Patient has the ability and will to participate during study period.
Exclusion criteria
Exclusion criteria: 1) Patient who received renal replacement therapy 2) Patient who was on special diets or drugs that were known to modulate drug metabolizing enzymes or affect absorption, distribution, metabolism and excretion of drug 3) Patients judged not eligible for the study after reviewing the clinical laboratory results or other reasons by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clearance of sufentanil | — |
Secondary
| Measure | Time frame |
|---|---|
| Concentration of sufentanil at steady state | — |
Countries
Korea, Republic of
Contacts
Gachon University Gil Medical Center