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A Study on the mechanism of acupuncture stimulation on cognitive reserve using machine learning and neuroimaging techniques

A Study on the mechanism of acupuncture stimulation on cognitive reserve using machine learning and neuroimaging techniques

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008719
Enrollment
60
Registered
2023-08-18
Start date
2023-08-22
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : In the study group, stainless needle (0.25mm*40mm, eastern acupuncture) is used to induce deqi sensation in acu-points associated with cognitive functions such as GV20, EX-HN1, KI3, S

Sponsors

Sangji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Those who aged 19 or older who show a decrease in cognitive function (MMSE-K<24, MoCA-K<23) and who have been diagnosed with mild cognitive impairment or mild/moderate dementia of CDR (clinical conditioning) <3 - Those who has heard a detailed explanation of this examination and has agreed in writing or who has decided to participate in this experiment after hearing a sufficient explanation by his legal representative - Those who can successfully carry out this study

Exclusion criteria

Exclusion criteria: - Severe dementia with CDR=3 - Patients with cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction - A person whose cognitive function has deteriorated due to other primary causes - Patients with severe internal diseases such as liver, heart, and kidney disease - A person who has a history of epilepsy, alcohol or drug addiction, or who is taking psychiatric drugs - Other cases where the researcher determines that it is inappropriate for this study

Design outcomes

Primary

MeasureTime frame
Differences of cortical activities before and after acupuncture stimulation in the study and control groups

Secondary

MeasureTime frame
Differences of cortical activities between groups according to cognitive reserve proxies;Brain activation areas associated with cognitive reserve indicators;Differences of cortical activities between cognitive impairment group and normal aging groups

Countries

Korea, Republic of

Contacts

Public ContactDong Hyuk Lee

Sangji University

neurohani_ldh@sangji.ac.kr+82-33-730-0664

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026