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Effects of exercise in the elderly with sarcopenia

Exploring myokine, immunocytes and thigh volume interactions and investigating the changes in re-variables after 12 weeks’ exercise in older adults with sarcopenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008712
Enrollment
74
Registered
2023-08-18
Start date
2025-05-22
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : Participants were provided with an intervention program designed to perform 50–120 minutes of exercise (such as hiking) per day, 2–3 days per week for 12 weeks, in accordance with the str

Sponsors

Hanseo University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The participants in this study resided in a single senior living community and were part of a cohort study targeting older adults with sarcopenia who had not engaged in regular exercise for six months. In the first phase of the study, 500 participants were planned for recruitment; however, 437 were enrolled, and the presence of sarcopenia as well as its associations with various variables were investigated. In the second phase, participants from two senior living communities selected from the initial cohort were randomized in a double-blind manner, resulting in a total of 87 recruits. After excluding 13 participants who did not meet the inclusion criteria, 74 individuals capable of performing forest hiking as an intervention involving resistance and aerobic exercise were allocated, with 37 assigned to the experimental intervention group and 37 to the control group.

Exclusion criteria

Exclusion criteria: In the 1st study, there are no specific exclusion criteria since participants are pre-screened to match the objectives of the research. However, as stated in the "Research Participant Information and Consent Form," participants have the right to discontinue their participation at any point during the experiment if they no longer wish to be involved. In the 2nd study, participants were excluded if they had undergone weight loss treatments, were taking medications that could influence body composition, or had received surgical interventions more than one year prior to the start of the study. Additionally, individuals with a history of cardiovascular or cerebrovascular disease, cancer, or psychiatric disorders were not eligible for participation.

Design outcomes

Primary

MeasureTime frame
The variables of interest in this study include sarcopenia variables, myokines, innate immune cells, adaptive immune cells, and thigh muscle volume.;Muscle oxygen saturation, physiological variables, and immune variables (myokines, innate and adaptive immune cells) in response to intense mountain hiking

Secondary

MeasureTime frame
Daily calorie intake, daily activity, sleep duration;Muscle oxygen saturation

Countries

Korea, Republic of

Contacts

Public ContactYong-Seok Jee

Hanseo University

jeeys@hanseo.ac.kr+82-41-660-1028

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Apr 30, 2026