Comparison of efficacy of anesthetics during cholecystectomy

Comparison of quality of recovery and analgesic effect between remimazolam and desflurane during laparoscopic cholecystectomy : randomized single-blind study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0008688

Enrollment

Registered

2023-08-08

Start date

2023-08-16

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The Remimazolam group, anesthesia is induced with remimazolam 6 mg/kg/hr (intravenous), and maintained with remimazolam 1mg/kg/hr during surgery. In the desflurane group, anesthesia is induced

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing laparoscopic cholecystectomy who are between 20 and 70 years of age and ASA(American Society of Anesthesiologists) physical status classification 1 or 2.

Exclusion criteria

Exclusion criteria: Patients with a history of hypersensitivity or adverse reactions to midazolam, propofol, or rocuronium; patients taking narcotic analgesics; patients with psychiatric conditions such as depressive disorders or schizophrenia; patients with a BMI > 30; creatinine > 2.0 mg/dl; platelet count 40 seconds; prothrombin time (PT INR) > 1.5.

Design outcomes

Primary

Measure	Time frame
QoR-15 score (Quality of Recovery-15 score)	—

Secondary

Measure	Time frame
amount of IV-PCA(IntraVenous-Patient Controlled Analgesia) used;Timing, type and amount of analgesics additionally administered;patient satisfaction for pain control;Nausea and vomiting	—

Countries

Korea, Republic of

Contacts

Public ContactSooho Lee

Catholic Kwandong University International St.Mary's Hospital

rysooho84@gmail.com+82-32-290-3586

Outcome results