Effect of Dexmedetomidine on duration of Intraoperative Hypotension During noncardiac Surgery under general anesthesia in patients with atrial fibrillation

Effect of Dexmedetomidine on duration of Intraoperative Hypotension During noncardiac Surgery under general anesthesia in patients with atrial fibrillation: a randomized double blind study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008670

Enrollment

100

Registered

2023-08-01

Start date

2023-07-26

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Commonly, general anesthesia is performed under the same conditions for anesthetic, body temperature, and oxygen fraction, which can affect the hemodynamic response during surgery. Anesthesia i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Atrial fibrillation patients aged 20 years or older who need non-cardiac surgery for more than 1 hour under general anesthesia (Patients aged 20 years or older) - ASA class II - III - A person who consented to the clinical trial and signed the informed consent form

Exclusion criteria

Exclusion criteria: - Cardiac conduction disorder (atrioventricular block, heart block) - If bradycardia of less than 50 beats per minute is confirmed - Patients participating in other studies at the same time - When regional wall motion abnormality is observed on echocardiography - If there is a history of side effects due to the use of the above anesthetic or contraindication (a patient who is expected to have an allergic reaction to the above drug) - A person who is judged to be inappropriate to participate in a clinical trial according to the judgment of the researcher

Design outcomes

Primary

Measure	Time frame
Time Weighted Average (<65mmHg)	—

Secondary

Measure	Time frame
Monitoring time per patient;Total number of hypotensive events in dataset;Total duration of hypotensive events per patient;Average duration of each hypotensive event;Mean MAP under 65mmHg per patient;Area under 65mmHg for MAP per patient (AUT);Total number of events when a patient is under 50mmHg;total time above 100 heart rate;maximum pain score;Total use of narcotic analgesics;Nausea and vomiting;Occurrence of cognitive dysfunction;level of consciousness;reoperation;inhospital stay days	—

Measure

Time frame

Monitoring time per patient;Total number of hypotensive events in dataset;Total duration of hypotensive events per patient;Average duration of each hypotensive event;Mean MAP under 65mmHg per patient;Area under 65mmHg for MAP per patient (AUT);Total number of events when a patient is under 50mmHg;total time above 100 heart rate;maximum pain score;Total use of narcotic analgesics;Nausea and vomiting;Occurrence of cognitive dysfunction;level of consciousness;reoperation;inhospital stay days

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Countries

Korea, Republic of

Contacts

Public ContactJISUN CHOI

Samsung Medical Center

luck8909@naver.com+82-2-3410-2470

Outcome results