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Relationship between immunologic changes and sarcopenia in the recovery process of elderly colon cancer patients and the effect of sarcopenia on recovery

Relationship between immunologic changes and sarcopenia in the recovery process of elderly colon cancer patients and the effect of sarcopenia on recovery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008630
Enrollment
40
Registered
2023-07-18
Start date
2023-07-28
Completion date
Unknown
Last updated
2023-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(additional blood test) : The treatment process is the same as other patients who underwent colon resection for colorectal cancer at Asan Medical Center in Seoul, and blood tests (-WBC, lymphocy

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Histologically confirmed colon adenocarcinoma of colon 2) No accompanying cancer 3) No distant metastasis 4) When surgical resection is performed 5) A person who has signed an agreement 6) Adults over the age of 20

Exclusion criteria

Exclusion criteria: 1) Accompanying cancer 2) Distant metastasis 3) No pre or postoperative imaging 4) A pregnant woman or a lactating woman 5) Currently or recently (within 28 randomized days) receiving another clinical trial medication or participating in another clinical trial 6) Mignant tumors in other tissues within the last 5 years 7) In the case of familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer

Design outcomes

Primary

MeasureTime frame
Postoperative hospitalization period: day of surgery - discharge date, postoperative complications: Infectious - wound complications, intra-abdominal inflammation, urinary tract infection, pneumonia, clostridium difficile infection/non-infectious - intestinal obstruction, bleeding, deep vein thrombosis

Secondary

MeasureTime frame
- Immune factor absolute value difference: IL-6, TNF-a, NK cell (difference between groups) - Differences in immune factor changes: IL-6, TNF-a, and NK cell changes by measurement period (difference between groups) - Differences in immune factors between myosteatosis and myopathy: Comparison of IL-6, TNF-a, NK cell absolute values and degree of change between myosteatosis and myopathy - Survival rate and recurrence rate in the elderly group: Comparison of survival rate and recurrence rate at the time of one or three years after surgery (by presence of immune factor,myosteatosis, and myopathy in the elderly group)

Countries

Korea, Republic of

Contacts

Public ContactBYEO LEE LIM

Asan Medical Center

limbl0731@naver.com+82-2-3010-3510

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026