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Evaluation of the Therapeutic Effects of a Combination Drug Containing Amlodipine, Losartan, Rosuvastatin, and Ezetimibe in Patients with Coexisting Hypertension and Dyslipidemia

A multi-center, prospective observational study to evaluate the effectiveness of a single-pill combination of amlodipine, losartan, rosuvastatin, and ezetimibe in patients with hypertension and dyslipidemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0008610
Enrollment
550
Registered
2023-07-14
Start date
2022-12-07
Completion date
Unknown
Last updated
2023-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patient diagnosed with essential hypertension and primary hypercholesterolemia, scheduled for treatment with a combination medication containing amlodipine, losartan, rosuvastatin, and ezetimibe. 2.Patient diagnosed with essential hypertension or primary hypercholesterolemia, currently receiving treatment with antihypertensive or lipid-lowering medications, planning to switch to a combination medication containing amlodipine, losartan, rosuvastatin, and ezetimibe.

Exclusion criteria

Exclusion criteria: 1.According to the approval indications, the combination medication containing losartan and amlodipine should not be administered in cases where there are contraindications specified. 2.The statin class medications (such as rosuvastatin, atorvastatin) and ezetimibe should not be administered in cases where there are contraindications specified. 3.Patients with suspected secondary hyperlipidemia or secondary hyperlipidemia, such as nephrotic syndrome, proteinuria, obstructive liver disease, Cushing's syndrome, etc. 4.If the patient has received investigational drugs for clinical trials within 4 weeks prior to the registration date, or plans to participate in other clinical trials during the study period.

Design outcomes

Primary

MeasureTime frame
The proportion of patients whose blood pressure (Systolic Blood Pressure, SiSBP; Diastolic Blood Pressure, SiDBP) is controlled according to the target blood pressure guidelines of the '2018 Hypertension Treatment Guidelines' at 12 weeks

Secondary

MeasureTime frame
The scores (or change in scores) of the Medication Satisfaction Questionnaire (MSQ), as assessed by patients at the 12-week time point.

Countries

Korea, Republic of

Contacts

Public ContactMin ku Chon

Pusan National University Yangsan Hospital

ki0106@hanmail.net+82-55-360-1459

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026