None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 20-69 with diarrhea-predominant or constipation-predominant irritable bowel syndrome.
Exclusion criteria
Exclusion criteria: Monk, history of irritable bowel syndrome (constipation-predominant), history of inflammatory bowel disease, history of colorectal cancer, history of gastrointestinal resection, abnormal blood test (liver function test: AST or ALT more than 1.5 times the normal limit, total bilirubin increase of more than 1.5mg/dL, CCr < 30 mL/min, platelets less than 100,000, PT/aPTT increase of more than 20% of the normal upper limit), uncontrolled hypertension and diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom score for IBS (IBS-SSS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal gut microbiome | — |
Countries
Korea, Republic of
Contacts
Dongguk University Ilsan Hospital