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Development of early dementia imaging marker by using a quantitative susceptibility mapping (QSM) and blood brain barrier (BBB) permeability imaging

Development of early dementia imaging marker by using a quantitative susceptibility mapping (QSM) and blood brain barrier (BBB) permeability imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0008510
Enrollment
75
Registered
2023-06-09
Start date
2017-08-09
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Konkuk University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Age 45 to 80 years old. - Individuals who have agreed to participate in the clinical trial and voluntarily signed the written informed consent form. - Patients who clinically correspond to the normal aging group or patients who meet the clinical diagnostic criteria for Mild Cognitive Impairment according to the 2011 NIA-AA (National Institute on Aging-Alzheimer's Association) guidelines. - Primarily, patients who have undergone an amyloid PET scan, if possible, are the primary targets.

Exclusion criteria

Exclusion criteria: Exclusion criteria include individuals with a history of drug addiction, past or current neurological, psychiatric, neurosurgical diseases, or head trauma. Those who have taken psychiatric medications at doses higher than the therapeutic range that could affect brain waves in the past three months are also excluded. The study targets only individuals found to be free from dementia, based on a medical history survey, neurological examination, and cognitive function test conducted by a neurology specialist.

Design outcomes

Secondary

MeasureTime frame
Temporal changes in susceptibility (brain iron) and BBB permeability.

Primary

MeasureTime frame
susceptiblity (brain iron), BBB permeability

Countries

Korea, Republic of

Contacts

Public ContactWon Jin Moon

Konkuk University

mdmoonwj@naver.com+82-2-2030-7682

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026