None listed
Conditions
Interventions
Drug : During the period of adjuvant chemotherapy (6 months), chemotherapy and administration of Megestrol acetate 500mg/pack were administered concurrently.
The dose of Megays is determined by the re
Sponsors
Pusan National University Yangsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) 19 years of age or older 2) Radical surgery for gastric cancer (R0 resection) 3) Stage II or III 4) Patients planning to receive adjuvant chemotherapy 5) Weight loss = 5% in the last 6 months 6) Appetite NRS score = 4 7) The patient accepts weight loss as a problem 8) I fully understand the informed consent and sign it by hand 9) A person who understands the clinical trial contents, is cooperative with the trial process, and is judged to be able to participate until the end of the study
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women 2) For gastric cancer, palliative surgery was performed instead of radical complete resection (R1 or R2 surgery). 3) Obesity (BMI =25 Kg/m2) 4) If there is a history of deep vein thrombosis or pulmonary thromboembolism 5) When it is judged that the researcher cannot comply with the requirements of the clinical trial protocol or has no intention to comply.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Planned chemotherapy cycle completion rate | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Relative dose intensity of chemotherapy, 2) Maximum chemotherapy dose reduction, 3) Quality of life (EQ5D), 4) Weight change, 5) Appetite NRS, 6) Adverse reactions, 7) Total prescription amount of megestrol. | — |
Countries
Korea, Republic of
Contacts
Public ContactSO YEON OH
Pusan National University Yangsan Hospital
Outcome results
None listed