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A comparison of quetiapine and risperidone in patients with delirium in ICU: a randomized controlled trial

A comparison of quetiapine and risperidone in patients with delirium in ICU: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008456
Enrollment
52
Registered
2023-05-22
Start date
2023-05-15
Completion date
Unknown
Last updated
2023-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : This study will be conducted on delirious patients admitted to the intensive care unit of the internal medicine department of Chung-Ang University Hospital. Patients with delirium selected base

Sponsors

Chung-Ang Univerisity Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients who have been diagnosed with delirium by a psychiatrist based on DSM-5 diagnostic criteria 2) Patients confirmed positive for delirium in Confusion Assessment Method-Intensitve Care Unit (CAM-ICU)

Exclusion criteria

Exclusion criteria: 1) People with acute complex neurological diseases (active seizure, brain tumor, acute hemorrhea, etc.) 2) Patients with a history of extrapyramidal diseases such as Parkinson's disease or Neuroleptic Malignant Syndrome (NMS) 3) Baseline QTc interval > 500 4) Patients diagnosed with major neurocognitive disorder (dementia) 5) Patients with a history of psychosis 6) Patients who are considered to have delirium due to alcohol or substance/drug induction and withdrawal 7) Patients who have history of administering antipsychotics within 48 hours 8) Patients who are unable to respond to verbal or physical stimulation due to hearing loss, visual loss, etc 9) Patients who are pregnant or lactating

Design outcomes

Primary

MeasureTime frame
Confusion Assessment Method-Intensive Care Unit (CAM-ICU)

Secondary

MeasureTime frame
Delirium Rating Scale-R-98 (DRS-R-98), Intensive Care Delirium Screening Checklist (ICDSC), Modified Simpson-Angus scale (M-SAS)

Countries

Korea, Republic of

Contacts

Public ContactNa Yeon Kim

Chung-Ang Univerisity Hospital

ny8953@cauhs.or.kr+82-2-6299-1508

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026