None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Among patients who have visited Seoul National Dental Hospital, subjects who are in need of oral examinations. ? Adult male and female patients between the ages of 19-75, have healthy or periodontally compromised teeth.
Exclusion criteria
Exclusion criteria: ? Subjects who fall under periodontitis grade B, when the tooth with most severe bone loss is used to calculate the value of % bone loss/age. ? Subjects who have taken antibiotics within the past 3 months. ? Subjects who have taken immunosuppressants (methotrexate, leflunomide, tacrolimus, cyclosporin, azathioprine) or corticosteroids (oral or IV injection) within the past 3 months. ? Subjects with uncontrolled hypertension of diabetes. ? Subjects with severe conditions relating to, or concomitant cardiovascular disease, respiratory disease, kidney disease, liver disease, blood system disease and neuropsychiatric disease. ? Subjects with hyperthyroidism or hypothyroidism. ? Pregnant women. ? Subjects with autoimmune diseases. ? Subjects with an ongoing disease or history of malignant tumors in the jaw bone. ? Patients with ongoing issues or history of alcohol or drug abuse within 1 year. ? Subjects with oral ulcers, Herpes simplex or Herpes zoster, fungal or bacterial infections, or any other inflammatory conditions affecting the oral mucosa unrelated to periodontitis. ? Other cases in which the subjects’ participation may be considered inappropriate due to ethical reasons or may compromise the results of research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| genome-wide information | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing pocket depth, gingival recession, clinical attachment level, gingival index, plaque index), tooth loss, bleeding on probing, tooth mobility, furcation involvement, Alveolar bone loss at the mesial and distal | — |
Countries
Korea, Republic of
Contacts
Seoul National University Dental Hospital