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Genome-wide association study of periodontitis in the Korean population

Analysis of genetic information and single nucleotide polymorphisms(SNPs) in Korean periodontitis patients with genome-wide association study(GWAS)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0008436
Enrollment
100
Registered
2023-05-16
Start date
2023-04-05
Completion date
Unknown
Last updated
2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Seoul National University Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? Among patients who have visited Seoul National Dental Hospital, subjects who are in need of oral examinations. ? Adult male and female patients between the ages of 19-75, have healthy or periodontally compromised teeth.

Exclusion criteria

Exclusion criteria: ? Subjects who fall under periodontitis grade B, when the tooth with most severe bone loss is used to calculate the value of % bone loss/age. ? Subjects who have taken antibiotics within the past 3 months. ? Subjects who have taken immunosuppressants (methotrexate, leflunomide, tacrolimus, cyclosporin, azathioprine) or corticosteroids (oral or IV injection) within the past 3 months. ? Subjects with uncontrolled hypertension of diabetes. ? Subjects with severe conditions relating to, or concomitant cardiovascular disease, respiratory disease, kidney disease, liver disease, blood system disease and neuropsychiatric disease. ? Subjects with hyperthyroidism or hypothyroidism. ? Pregnant women. ? Subjects with autoimmune diseases. ? Subjects with an ongoing disease or history of malignant tumors in the jaw bone. ? Patients with ongoing issues or history of alcohol or drug abuse within 1 year. ? Subjects with oral ulcers, Herpes simplex or Herpes zoster, fungal or bacterial infections, or any other inflammatory conditions affecting the oral mucosa unrelated to periodontitis. ? Other cases in which the subjects’ participation may be considered inappropriate due to ethical reasons or may compromise the results of research.

Design outcomes

Primary

MeasureTime frame
genome-wide information

Secondary

MeasureTime frame
Probing pocket depth, gingival recession, clinical attachment level, gingival index, plaque index), tooth loss, bleeding on probing, tooth mobility, furcation involvement, Alveolar bone loss at the mesial and distal

Countries

Korea, Republic of

Contacts

Public ContactHYUNYOUNG SONG

Seoul National University Dental Hospital

1030shy@naver.com+82-2-2072-3071

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026