Validation of AI based Multimodal Information Images Generation Technique using Early Dynamic Amyloid PET Imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008435

Enrollment

Registered

2023-05-16

Start date

2023-04-13

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1) Additional acquisition of dynamic images for 40 minutes immediately after slow bolus intravenous injection of radioactive trackers during amyloid PET 2) Obtain dynamic images for 40 minutes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - 41-80-year-old adult - Patients with suspected cognitive impairment, such as subjective cognitive impairment, mild cognitive impairment, Alzheimer's disease, and other degenerative brain diseases, and requested an amyloid PET test - A person who has signed and sealed a prior consent form in accordance with the relevant statutes or his/her representative;

Exclusion criteria

Exclusion criteria: - Patients who are unable to stably perform PET/CT imaging due to lack of cooperation, such as claustrophobia, motor dysfunction, anxiety disorder, seizures,etc. - Subjects are accompanied by severe and/or unregulated and/or unstable medical conditions (e.g., congestive heart failure, acute myocardial infarction, severe lung disease, chronic kidney disease, or chronic liver disease) at the discretion of the tester. - Where it is judged by the tester that it will be impossible for the subject to complete data collection for clinical trials due to personal circumstances or other reasons; - a pregnant or lactating woman

Design outcomes

Primary

Measure	Time frame
Consensus rate of visual/quantitative determination of amyloid positive/negative of virtual amyloid images generated using artificial intelligence in early dynamic images and actually obtained delayed amyloid PET images	—

Secondary

Measure	Time frame
Correlation between virtual amyloid images generated using artificial intelligence in early dynamic images, virtual brain metabolic images, and local brain region intake ratio (SUVR) measured from actual obtained delayed amyloid PET and FDG PET images.	—

Countries

Korea, Republic of

Contacts

Public ContactSung Changhwan

Asan Medical Center

sungch26@amc.seoul.kr+82-2-3010-1517

Outcome results