None listed
Conditions
Interventions
Others : Participants will be randomly assigned to PC6 electroacupuncture-median nerve stimulation (EA-MNS) group or TF4 electroacupuncture-vagus nerve stimulation (EA-VNS) group or usual care (UC) gr
Sponsors
Daejeon Korean Medicine Hospital of Daejeon University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants who 1) aged 19-70 years old 2) diagnosed of anxiety disorder by Structured Clinical Interview for DSM-5 including social anxiety disorder, agoraphobia, panic disorder, generalized anxiety disorder, other specified anxiety disorders and unspecified anxiety disorder 3) voluntarily decide to participate in this clinical study and signed the written consent form 4) are able to complete electroacupuntrue-neural stimulation treatments for 8 weeks
Exclusion criteria
Exclusion criteria: 1) risk of suicide with C-SSRS > 4 2) current or past history of schizophrenia or bipolar disorder 3) separation anxiety disorder, elective mutism, substance-induced anxiety disorder, anxiety disorder due to medication, or anxiety disorder due to other medical conditions 4) history of acupuncture treatment within 4 weeks 5) alcohol or other substance use disorders within 8 weeks 6) history of cerebrovascular diseases, brain tumor, or traumatic brain injury 7) history of neurological or systemic diseases that may affect central nervous system 8) unstable medical conditions requiring inpatient treatment 9) usage of a pacemaker 10) indications for acupuncture treatment being inappropriate or unsafe (e.g., acupuncture-associated vasovagal response or tissue damage due to acupuncture) 11) participation in medication or other intervention in other clinical trials within 1 month 12) pregnant or lactating women or not using medically acceptable contraception during the study period 13) inappropriate for enrollment due to other reasons as determined by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Rating Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Beck Anxiety Inventory;Beck Depression Inventory;Patient Health Questionnaire-15;WHO QoL assessment instrument abbreviated version;Penn State Worry Questionnaire (only for Generalized anxiety disorder, Other specified anxiety disorders, Anxiety disorder, unspecified);The Panic Disorder Severity Scale (only for Panic disorder and Agoraphobia);Liebowitz Social Anxiety Scale (only for Social anxiety disorder) | — |
Countries
Korea, Republic of
Contacts
Public ContactJieun Kim
Korea Institute of Oriental Medicine
Outcome results
None listed